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Gout Sufferers - Ease Your Pain |
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A swollen big toe and a hobbled gait - finally, excruciating pain sends you to fill a prescription for allopurinol, the standard drug for treating gout. Are there natural remedies you can use to ease gout suffering in addition to or instead of the pharmaceutical? While gout cannot be cured, it can be controlled with medication, herbs, diet and nutritional supplements. Since ancient times people have suffered from the pain and swelling caused by a precipitation of uric acid crystals (monosodium urate) in joints, tendons, kidneys and other tissues. Diet was always blamed - particularly rich foods such as gravies, organ meats and other proteins - but we now know gout can result from a number of genetic disorders that cause overproduction or impaired excretion of uric acid. Gout affects between three and five adults per thousand in the general population, but more than 95 percent of cases occur in men older than 30. This means roughly one in 100 adult men have gout. Some 70 percent of gout patients have an overproduction of uric acid, while about 30 percent have problems eliminating it from their bodies. The result of either situation is excess uric acid that crystallizes in joints and causes painful inflammation and severe arthritic symptoms. It is not clear what makes the uric acid precipitate in the joints, but it is not simply because there is too much present. Some patients can have chronically elevated uric acid levels with no other gout symptoms. Interestingly, the first joint of the big toe is affected in almost half of all first attacks, and there is a 90 percent chance that gout patients will have an attack in their toe at some time. Why the toe? Uric acid has a lower saturation point at lower temperatures, which may explain why deposits tend to form in the cooler extremities including the toe, or the top of the ear. Uric acid is the normal form in which biochemicals called purines are excreted after they are digested and metabolized. Purines are components of the nucleic acids DNA and RNA. In fact, uric acid is not all bad. It has antioxidant activity nearly equivalent to vitamin C, prompting some researchers to speculate that genes causing high levels of uric acid were not selected against because the uric acid helps protect against oxidative damage to cells. Dietary Management of Uric Acid It is impossible to completely eliminate purine metabolism, nor would anyone want to, because a large percentage of purines are generated as the body recycles its own tissue proteins. But dietary recommendations for gout management limit purine intake, and eliminate nearly all protein, especially meat. The high-purine foods to limit or avoid are organ meats, which are rich in nucleic acids, as well as anchovies, baker's and brewer's yeast, herring, mackerel, red meat, sardines and shellfish. Poultry and white fish--which also contain purines but have less dense muscle fibers, a different protein composition and more water per unit weight than red meat and dark fish - are better choices but should not be eaten in excess either. Legumes, especially peanuts, should also be limited or avoided because of their purines content. Nutritional yeast, supplements with DNA, RNA or organ tissue extracts such as thyroid or thymus can also pose a risk if taken regularly. Alcohol consumption exacerbates gout by reducing uric acid elimination from the body and slightly increasing uric acid production. Beer and wine are higher in purines than other alcoholic beverages because of their yeast residues. Heavy drinkers are more likely to have gout than those who drink less. Very high intakes of fructose - 25 to 30 percent of calories - can also elevate uric acid, so those with gout should minimize fructose intake, namely high fructose corn syrup, which is present in many processed foods and beverages. A gout-prevention diet should emphasize complex carbohydrates and plenty of water. Adequate fluid intake dilutes the urine and promotes excretion of uric acid. The more diluted the urine, the less risk there is for developing kidney stones, which can be a problem for gout patients. Herbal Options The enzyme xanthine oxidase catalyzes the last step in the conversion of purines to uric acid. Allopurinol, the medication prescribed for gout prevention, is a xanthine oxidase inhibitor. In test tube studies, xanthine oxidase is inhibited by the flavonoids luteolin and apigenin nearly as well as it is by allopurinol. The flavonoids chrysin, baicalein, isorhamnetin, and several caffeic acid esters are also effective. Bioflavonoids (water-soluble plant pigments), are part of a large group of antioxidant phytochemicals. Chamomile (Matricaria recutita), chiso (Perilla frutescens), many mints (Mentha spp.) and yarrow (Achillea millefolium) are rich in luteolin, apigenin and caffeic acids. Those bioflavonoids can also be found in carrots. There are no clinical studies proving these herbs can prevent gout recurrence, but they are safe and worth a try. Baikal skullcap (Scutellaria baicalensis) and Taiwanese skullcap (S. rivularis) contain baicalein as well as several other anti-inflammatory flavonoids. Both the isolated flavonoids and herbal extracts from skullcap have shown effectiveness against paw inflammation in mice and are used traditionally for chronic inflammatory conditions and liver disorders. A combination of herbs is often recommended as a preventive measure: three capsules each of standard dose skullcap, chamomile and yarrow. Incorporating chiso leaf and peppermint tea is also a good idea.
Other xanthine oxidase inhibitors, albeit weak ones, are anthocyanidins and proanthocyanidins. Cherries, grapes, blueberries and bilberries contain both these antioxidants. Eating cherries has been shown to lower uric acid levels and prevent gout attacks. Gout sufferers should try to incorporate fresh cherries into their daily diet. In addition to berries, extracts of bilberry (Vaccinium myrtillus), grape seed (Vitis vinifera) or pycnogenol (Pinus maritima) are rich sources of anthocyanidins and proanthocyanidins. Another suggested alternative to allopurinol is celery (Apium graveolens) seed extract. Though there is no research to support this medicinal use, celery is known to contain at least 26 anti-inflammatory compounds. These anti-inflammatory qualities explain at least part of celery's beneficial effects against gout. The celery plant has apigenin, but it is not concentrated in the seeds, so if the seeds do inhibit xanthine oxidase, the mechanism is currently unknown. Some gout patients who take 450 mg of celery seeds per day have not had a gout attack since beginning this treatment. During acute gout attacks, herbal anti-inflammatories including boswellia (Boswellia serrata), curcumin (Curcuma longa), devil's claw (Harpagophytum procumbens) and yucca (Yucca spp.) can be tried instead of aspirin or arthritis drugs. Nutrients to Keep Gout at Bay Though not as useful as some of the herbal remedies for easing pain, supplements can be an important part of a preventive plan.
Omega-3 fatty acids can be useful in the treatment of gout. Eicosapentaenoic acid (EPA – one of the two active components of fish oils) inhibits production of the inflammatory leukotrienes, which are responsible for much of the inflammation and tissue damage that occurs with gout. Folic acid has been shown to inhibit xanthine oxidase (more potently than the standard pharmaceutical, allopurinol). Positive results have been reported by gout sufferers using a daily dosage of 10 - 40 mg of folic acid.
High doses of niacin, greater than 50 mg daily, are not recommended for people with gout because niacin competes with uric acid for bodily excretion. Vitamin C in doses greater than 3,000 mg is also contraindicated for gout sufferers because it may increase uric acid in some people. Gout should not be left untreated. Over time, microscopic crystals of uric acid can damage organs, particularly the heart and kidneys. Increased uric acid levels can also increase the risk of kidney stones. Luckily, modest dietary modifications and a carefully planned supplements program can obviate prescriptions and lessen the suffering from gout attacks.
RELATED PRODUCTSNatures Goodness Joint Formula Cherry Juice Concentrate 1LDaily consumption of Cherry Juice may be beneficial in maintaining healthy joints, joint function, and aiding in the treatment of arthritis and gout.
Blooms Celery & Juniper 3000mg 70 CapsulesCelery: is one of the most widely utilised herbs for conditions such as arthritis, rheumatism and gout, having the ability to encourage elimination of acid crystals that have collected in the joints.
Fusion Health Pain & Inflammation 60 TabletsMay assist in alleviating the symptoms of osteoarthritis and rheumatoid arthritis, fibromyalgia, bursitis, tendonitis, scatica and gout.
Blackmores Grape Seed Forte 30 TabletsA powerful herbal antioxidant and free radical scavenger that is a rich source of plant flavonoids called oligomeric proanthocyanidins (OPCs). Grape seed also provides protection against cellular damage by free radicals.
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